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Testosterone is produced by the testes in response to signals sent out by the hypothalamus and pituitary gland (located at the base of the brain). However, in some men, the testes may be unable to fulfill the body's testosterone levels.
Low testosterone has many possible causes, including genetic abnormalities, injury to the testes, testicular infection, hormonal disorders, or systemic diseases (eg, HIV/AIDs, chronic liver and kidney disease, diabetes). Additionally low testosterone has been associated with insulin resistance, metabolic syndrome, and other chronic comorbid conditions.
A medical condition, "hypogonadism," which can result in low testosterone, is not a natural part of aging. Hypogonadism affects millions of men in the United States. Its prevalence increases with age, and it is underdiagnosed and undertreated.
Androderm® is used to treat adult males who have low or no testosterone.
IMPORTANT SAFETY INFORMATION
You should not use Androderm® if you have breast cancer, known or suspected prostate cancer, or if you have pre-existing heart, kidney, or liver disease. You should also not use Androderm® if you are a pregnant or breastfeeding woman, as testosterone may cause fetal harm. If you have an enlarged prostate (BPH), you should be monitored for worsening signs and symptoms. Women and children should not be exposed to Androderm®. Taking testosterone may lead to a condition in which there are no sperm in the semen, and if you have risk factors, may cause sleep apnea (abnormal pauses in breathing). Your healthcare provider should monitor you for prostate specific antigen (PSA), liver function, lipids, and blood parameters. The most common adverse events in a study of 36 patients treated with Androderm® were skin irritation (itching at the application site), application site blisters, and back pain.
Androderm® is available only by prescription.
To report suspected adverse reactions, contact Watson Pharmaceuticals, Inc. at 1-800-272-5525 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Please see full Prescribing Information.
Models are for illustrative purposes only.