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Androderm, Testosterone Transdermal System

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Why Should I Choose Androderm?

Androderm significantly improves sexual function, energy, and mood in men with low testosterone levels. And the patch minimizes the risk that testosterone may be passed on to others. The Androderm patch offers many special features.

Convenient, Once Daily Patch An Effective Therapy With Proven Benefits Safety Profile You Can Trust

Convenient, Once Daily Patch
 

Consistent, controlled delivery.
A convenient, once-daily non-scrotal patch delivers consistent testosterone throughout a 24-hour day. No need to worry about multiple daily doses. The body receives a steady, controlled testosterone supply, without a single, large surge. The benefit of sustained delivery means there may be less risk for ups and downs in mood, energy, or sexual desire.

Matches the body's rhythm.
The delivery rate matches the body's natural production. So throughout the day, testosterone levels follow the body's natural biorhythm. For example, in healthy young men, testosterone levels peak in the early morning hours; the patch matches this pattern. (The clinical significance of this natural delivery profile is unknown.)

Convenient and clean.
Small and unnoticeable, the patch can be worn under clothing and it doesn't attract attention. There's no waiting after application. You can wear it while showering, exercising, or during other strenuous physical activities. And there's minimal risk that testosterone will rub off on to other people, such as women or children.



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Safety Information

If you are over 55 years of age, treatment with androgens (such as testosterone) may increase the risk of benign enlargement of the prostate and may promote the growth of existing cancer of the prostate. While using Androderm, some patients may experience skin irritation at the application site. To reduce the risk of such irritation, the patch should not be applied to the same place more than once a week. If irritation occurs and persists in spite of rotating the patch, it may be ameliorated by applying 0.1% triamcinolone acetonide cream. Androderm must not be used by women. Androderm should not be used by men who have breast cancer or by men who are suspected to have cancer of the prostate. Also, Androderm should not be used by men who are hypersensitive to any of the patch components. Adverse events reported by > 5% of patients in clinical trials of Androderm (n=122): pruritus at application site, 37%; burn-like blister reaction under system, 12%; erythema at application site, 7%; vesicles at application site, 6%; prostate abnormalities, 5%. In geriatric patients, treatment with testosterone may increase the risk of developing benign prostatic hyperplasia and may promote the growth of existing prostate cancer. Androderm should not be applied over bony prominences or over areas subject to prolonged pressure. Androderm must not be used in women.

Please see Prescribing Information.

+ References

 

[1] Androderm® Physician Prescribing Information
[2] Androderm® Patient Prescribing Information
[3] Petak SM. ACCE Medical Guidelines for clinical practice for the evaluation and treatment of hypogonadism in adult male patients-2002 update. Endocr Pract 2002;8: 439-459.
[4] Meikle AW, Arver S, Dobs AS, et al. Pharmacokinetics and Metabolism of a Permeation-Enhanced Testosterone Transdermal System in Hypogonadal Men: Influence of Application Site - A Clinical Research Center Study. J Clin Endocrinol Metab1996;81:1832-1840.
[5] Kaufman JM, Vermeulen A. Declining gonadal function in elderly men. Bailiere's Clin Endocrinol Metab 1997;11:289-309.
Þ Includes free, albumin-bound, and SHBG-bound testosterone.
‡ As determined by equilibrium dialysis.
* Clinical significance is unknown.

 

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