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Androderm, Testosterone Transdermal System

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Why Should I choose Androderm?How Do I Use Androderm?How Do I Apply Androderm?
How Do I Use Androderm?
 

For complete instructions and information on how to use Androderm click here.

How to Use Androderm (Testosterone Transdermal System)

It is important that you read and follow these directions on how to use Androderm properly.

  1. Application Diagram Apply Androderm at the Same Time Every Evening: Unless your doctor tells you to use fewer or more patches, you should apply one (1) new Androderm 5 mg patch or two (2) new Androderm 2.5 mg patches every evening. This delivers approximately 5 milligrams of testosterone per day into the body, about the same amount of testosterone normally produced in men.
  2. Apply Androderm Each Evening, Between 8:00 p.m. and Midnight: This results in a daily cycle of testosterone levels similar to the pattern in healthy young men with normal levels of testosterone.
  3. Replace Every 24 Hours: Remove the Androderm patch(es) after 24 hours and apply new patch(es). Although gel remains in the patch, new patch(es) are required each day to maintain normal testosterone levels.
  4. Only Apply Androderm to Your Back, Abdomen, Thighs or Upper Arms: This way your body will absorb the correct amount of testosterone (see diagram).
  5. Apply Androderm to Clean and Dry Areas: Choose areas of the body where the patch will remain flat against the skin without excessive stretching or folding as you go about your normal activities. Avoid areas of skin that are oily, perspire heavily, or are covered with hair, since the patch may not stick tightly to these areas.
  6. Never Apply a Patch to Your Genitals (Scrotum), or to Damaged Skin: Apply Androderm only to healthy, normal skin. Never apply a patch to your genitals (scrotum), or onto skin areas with open sores, wounds or irritation.
  7. Avoid Application over Bony Areas: Applying Androderm to bony areas, such as the upper shoulder and the upper hip, or on a part of the body that could be subject to prolonged pressure during sleep or sitting may cause burn-like blisters to form under the patch.
  8. To Help Prevent Skin Irritation, Change Application Sites Regularly: When you remove a patch, do not put another patch back on that same spot for at least a week. If you experience mild skin irritation, it may be relieved with over-the-counter topical hydrocortisone cream, which your pharmacist can recommend. If you experience persistent irritation, please consult your doctor regarding additional treatment options.
  9. Maintain Normal Activities: A patch applied to clean, dry skin will remain in place during normal activities. Androderm may be worn during sex. Also, contact with water, such as showering or swimming, will not affect the patch. Strenuous exercise or excessive perspiration may loosen a patch or cause it to fall off.
  10. What to Do if a Patch Becomes Loose, or Falls Off: If the patch becomes loose, smooth it down again by rubbing your finger firmly around the edges. If a patch falls off before noon, replace it with a fresh patch and wear it until you apply fresh patch(es) that evening. If it falls off later in the day, do not replace it until you apply fresh patches that evening.

How Do I Apply Androderm?

 

Safety Information

If you are over 55 years of age, treatment with androgens (such as testosterone) may increase the risk of benign enlargement of the prostate and may promote the growth of existing cancer of the prostate. While using Androderm, some patients may experience skin irritation at the application site. To reduce the risk of such irritation, the patch should not be applied to the same place more than once a week. If irritation occurs and persists in spite of rotating the patch, it may be ameliorated by applying 0.1% triamcinolone acetonide cream. Androderm must not be used by women. Androderm should not be used by men who have breast cancer or by men who are suspected to have cancer of the prostate. Also, Androderm should not be used by men who are hypersensitive to any of the patch components. Adverse events reported by > 5% of patients in clinical trials of Androderm (n=122): pruritus at application site, 37%; burn-like blister reaction under system, 12%; erythema at application site, 7%; vesicles at application site, 6%; prostate abnormalities, 5%. In geriatric patients, treatment with testosterone may increase the risk of developing benign prostatic hyperplasia and may promote the growth of existing prostate cancer. Androderm should not be applied over bony prominences or over areas subject to prolonged pressure. Androderm must not be used in women.

Please see Prescribing Information.

+ References

 

[1] Androderm® Physician Prescribing Information
[2] Androderm® Patient Prescribing Information
[3] Petak SM. ACCE Medical Guidelines for clinical practice for the evaluation and treatment of hypogonadism in adult male patients-2002 update. Endocr Pract 2002;8: 439-459.
[4] Meikle AW, Arver S, Dobs AS, et al. Pharmacokinetics and Metabolism of a Permeation-Enhanced Testosterone Transdermal System in Hypogonadal Men: Influence of Application Site - A Clinical Research Center Study. J Clin Endocrinol Metab1996;81:1832-1840.
[5] Kaufman JM, Vermeulen A. Declining gonadal function in elderly men. Bailiere's Clin Endocrinol Metab 1997;11:289-309.
[6] Bhasin S et al., Testosterone Therapy in Adult men with Androgen Deficiency Syndromes: An Endocrine Society Clinical Practice Guideline, J Clin Endocrinol & Metab, June 2006,91(6)1999:1995-2010.
Þ Includes free, albumin-bound, and SHBG-bound testosterone.
‡ As determined by equilibrium dialysis.
* Clinical significance is unknown.

 

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